Medication-Induced Mitochondrial Damage

drug induced mitochondrial damage

Damage to mitochondria is understood to play a role in the development of a wide range of seemingly unrelated disorders such as schizophrenia, Alzheimer’s, cardiovascular disease, diabetes, and others. Mitochondrial damage is also a hallmark of ME/CFS and Fibromyalgia.

Common causes of mitochondrial dysfunction in ME/CFS and Fibromyalgia are numerous. They include:

  • Dysbiosis
  • Chronic viral infections
  • Metabolic dysfunction (poor insulin control, nutrient depletion)
  • Toxin exposure (metals, mold, other environmental factors)

Another cause of mitochondrial dysfunction that is less frequently mentioned is medication usage. Mitochondrial toxicity testing is NOT required by the FDA before a drug is approved. Medications can hinder mitochondria through direct or indirect mechanisms.

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Low Iron Linked with Muscle Health, Sleep Disorders, Mood, Stroke Risk, and Mitochondria

Do you have iron deficiency and not know it? Fatigue, weakness, and cold intolerance are common symptoms of low iron. Standard blood tests may not reflect early iron deficiency. There is, however, a special lab test that tells you how good your iron stores are even before extensive changes occur. This lab test is called serum ferritin. Serum ferritin levels reflect the actual amount of iron stores in the body. A depletion of iron stores indicates a functional deficiency and early iron deficiency, which can cause a variety of health disorders. There is more to low serum ferritin and iron deficiency than meets the eye.

Symptoms of Iron Deficiency

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7 Reasons to Get More Magnesium

7 Reasons to Get More Magnesium

Magnesium is the fourth most abundant mineral in your body, and is the reason why vegetables are green.  But few people fully appreciate the importance of this miraculous mineral. 

The human genome project reveals that 3,751 human proteins have binding sites for magnesium.[i]  And so far we know this one essential mineral activates over 350 biochemical processes in the body to keep things flowing.

Plants are green because they contain the light-harvesting molecule chlorophyll which bears a striking resemblance to human hemoglobin (with the difference that the latter contains an oxygen-binding iron atom and not magnesium).

Here are just seven good reasons to get more magnesium-rich foods in your diet today.

1. Prevent Migraines.

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Vitamin D – Why You are Probably NOT Getting Enough

http://www.precisionnutrition.com/wordpress/wp-content/uploads/2009/11/Fig-1-Vit-D.jpg

WHAT VITAMIN DO WE need in amounts up to 25 times higher than the government recommends for us to be healthy?

What vitamin deficiency affects over half of the population, is almost never diagnosed, and has been linked to many cancers, high blood pressure, heart disease, diabetes, depression, fibromyalgia, chronic muscle pain, bone loss, and autoimmune diseases like multiple sclerosis?

What vitamin is almost totally absent from our food supply?

What vitamin is the hidden cause of so much suffering that is so easy to treat?

The answer to all of these questions is vitamin D.

Over the last 10 years of my practice, my focus has been to discover what the body needs to function optimally. And I have become more interested in the role of specific nutrients as the years have passed.

Two recent studies in The Journal of Pediatrics found that 70 percent of American kids aren’t getting enough vitamin D, and this puts them at higher risk of obesity, diabetes, high blood pressure, and lower levels of good cholesterol. Low vitamin D levels also may increase a child’s risk of developing heart disease later in life. (more…)

Worth Repeating: Marijuana Is One of the Best-Studied Medicines In History

Ben Whalley, middle, with Dr Gary Stephens and Dr Claire Williams of Reading University at a secret cannabis farm in the south of England in the hope of producing a new treatment for epilepsy [Geoff Pugh/The Telegraph]

Ben Whalley, middle, with Dr Gary Stephens and Dr Claire Williams of Reading University at a secret cannabis farm in the south of England in the hope of producing a new treatment for epilepsy
[Geoff Pugh/The Telegraph]

Editor’s note: Welcome to Room 420, where your instructor is Mr. Ron Marczyk and your subjects are wellness, disease prevention, self actualization, and chillin’.

An overwhelming amount of very promising research has been gathered supporting the use of medical cannabis for many illnesses and diseases… and the evidence is now impossible to ignore.

Examples:

WorthRepeatingLogo“The endogenous cannabinoid system has revealed potential avenues to treat many disease states … Medicinal indications of cannabinoid drugs including compounds that result in enhance endocannabinoid responses (EER) have expanded markedly in recent years.”

“The wide range of indications covers … chemotherapy complications, tumor growth, addiction, pain, multiple sclerosis, glaucoma, inflammation, eating disorders, age-related neurodegenerative disorders, as well as epileptic seizures, traumatic brain injury, cerebral ischemia, and other excitotoxic insults.”

Source: “Cannabinoid drugs and enhancement of endocannabinoid responses: strategies for a wide array of disease states,” Current Molecular Medicine, September 2006

and…

[NORML]

[NORML] (more…)

10 Causes Of Fibromyalgia Your Doctor May Not Know About

It’s estimated that fibromyalgia affects approximately 10 million people in the United States. Fibromyalgia is classically characterized by chronic pain, particularly muscle pain, fatigue, sleep disturbances, brain fog or cognitive impairment, depression and painful tender points throughout the body.

Conventional medicine has yet to uncover the cause of fibromyalgia and only offers management of symptoms through pain medications and antidepressants.

Functional medicine, on the other hand, looks to find the root cause of fibromyalgia and other chronic diseases, treating the problem at the root level to restore the patient to health. As a functional medicine physician, I’ve helped many patients recover from fibromyalgia.  Below are the top ten root causes of fibromyalgia I see in my clinic.

1. Gluten intolerance

Gluten has been liked to more than 55 diseases and is often called the “big masquerader.” The reason for this is that the majority of gluten intolerance symptoms are not digestive in nature, but are instead neurological, such as pain, cognitive impairment, sleep disturbances, behavioral issues, fatigue and depression.

2. Candida overgrowth (more…)

Low vitamin D levels can alter your gene expression

Mon. Apr.1, 2013 by Blanche Levine

Antibiotic News(NaturalHealth365) Low vitamin D levels can be the most damaging influence on our genetic health, according to professor George Ebers, Action Medical Research professor of Clinical Neurology and one of the senior authors of published scientific research.

What are the capabilities of vitamin D?

Researchers, at the University of Oxford, have shown the extent in which vitamin D interacts with our DNA. The researchers found 2,776 binding sites from the vitamin D receptor along the length of the genome. These are the ones unusually concentrated near a number of genes associated with autoimmune conditions such as MS, Crohn’s disease, systemic lupus, rheumatoid arthritis and cancers such as, lymphocytic leukemia and colorectal cancer. (more…)

How Inflammation Affects Every Aspect of Your Health

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Dr. David M. Marquis, DC, DACBN

Inflammation controls our lives. Have you or a loved one dealt with pain, obesity, ADD/ADHD, peripheral neuropathy, diabetes, heart disease, stroke, migraines, thyroid issues, dental issues, or cancer?

If you answered yes to any of these disorders you are dealing with inflammation.

Sadly, most of us are suffering from one or more of these disorders but have no idea how to eliminate inflammation. Most doctors are utilizing pharmaceuticals in lieu of getting to the root cause.

It often seems extremely foreign to most people when they realize the majority of inflammatory diseases start in the gut with an autoimmune reaction which progresses into systemic inflammation. To truly be effective at managing or hopefully overcome a disease it needs to be addressed on all levels. Taking a look at where this process starts is the key.

Where Does Inflammation Begin? (more…)

Noradrenaline Strategy

Overview

If the Noradrenaline (NA) neurotransmitter communication channel is not working properly, you will feel tired. One can test this channel, using the following procedure.

1) Read
A) Click here to learn about brain chemistry.
B) Click
here to learn about the chemistry behind the Noradrenaline neurotransmitter.

2) Take A Tyrosine Challenge Test (more…)

5 Health Benefits of Sauna Use

Sauna Art: Pekka Halonen-Saunassa

If you’ve ever been in a sauna then you know first hand how rejuvenating and invigorating a good sweat can be. Sweating is a form of detoxification and there may be no better place to stimulate this process than in the sauna. Sauna therapy developed in the Scandinavian region, specifically Finland, and is used for bathing, improving ailments, and even as a setting for childbirth. To say the sauna is a foundational element of Finnish society would be an understatement, some even view it as a holy place and behave as they would in a church. It’s no wonder, more than just a place to feel good, the sweat inducing heat is also thought to improve many health problems including hypertension, fatigue, pain, and even addiction. (more…)