A February 2015 study reveals that supplementing with alpha-lipoic acid (ALA) can help boost weight loss efforts. ALA is an antioxidant that fights free radical damage throughout the body. It is also vital for the production of cellular energy.
In this study, researchers wanted to evaluate ALA supplementation—with and without the omega-3 fatty acid eicosapentaenoic acid (EPA)—on healthy overweight or obese women following a reduced-calorie diet.
The researchers randomly assigned the women to receive EPA, ALA, or EPA+ALA. A fourth group served as the control. All the groups also followed a low-calorie diet.
Before and at the conclusion of the intervention, all participants had their weight, body fat, body composition, blood pressure, glucose, insulin, cholesterol and levels of leptin and ghrelin measured.
The results showed that the women who took the ALA, either alone or along with EPA, experienced significantly higher weight loss than the EPA group or control.
The researchers concluded, “The intervention suggests that ALA supplementation alone or in combination with EPA may help to promote body weight loss in healthy overweight/obese women following energy-restricted diets.”
Huerta AE, et al. Obesity (Silver Spring). 2015 Feb;23(2):313-21.