Pleurotus Abalonus Protects Against Colon Cancer

Recently published research indicates that a species of mushroom—Pleurtous abalonus—may inhibit colon cancer.

An estimated 93,000 new cases of colon cancer and 40,000 new cases of rectal cancer will be diagnosed in 2015. Colon cancer affects the large intestine, while rectal cancer occurs in the last few inches of the colon. Together, colorectal cancer is the third most common cancer in both men and women.

In this study, researchers isolated the polysaccharides in P. abalonus and evaluated their effect on human colon cancer cell lines. (Polysaccharides are carbohydrates made of various sugar molecules bonded together.)

The polysaccharides exerted antioxidant and antiproliferative (halted rapid multiplication) activity on the cells. They also stimulated cancer cell apoptosis (death).

The researchers wrote that the polysaccharides found in P. abalonus may serve as “a potential novel dietary agent for human colon cancer chemoprevention.”

Ren D, et al. Chem Biol Interact. 2015 Jul 25;237:166-74.

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