Resveratrol and diabetics

RESVERATROL is a potent antioxidant found in red wine and has been shown to increase the life span and physical endurance in mammals. Resveratrol may enhance health and longevity via several mechanisms. One mechanism is by promoting the activation of sirtuins, a class of histone deacetylase enzymes (HDACs) involved in cell death and life-span regulation. Resveratrol has also been shown to regulate telomerase activity, thus protecting telomeres from damage. Until the more recent discovery of resveratrol’s life extending benefits, practicing a calorie restriction diet while maintaining good nutritional status was the only scientifically supported practice for extending the life span. The genetic pathways influenced by resveratrol are similar to those affected by a calorie restricted diet. For example, they both are associated with the long term activation of AMP-activated kinase (AMPK). Increased AMPK activity appears to lengthen lifespan by promoting insulin sensitivity.†

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