Horse Chestnut Protects Your Liver from Toxic LPS

The horse chestnut tree (Aesculus hippocastanum) produces a seed that is used as a dietary supplement extract. Horse chestnut seed extract (HCSE) is a rich source of a nutrient called aescin (also escin), which is believed to be its biologically active compound. Toxic and inflammatory lipopolysaccharide (LPS) is produced by bacterial infections. A new animal study shows that aescin can reduce the damage to the liver that LPS causes, expanding the value of this unique circulation-support nutrient.

Horse chestnut is in widespread use in Europe to assist a problem known as chronic venous insufficiency (CVI) as well as issues with varicose veins, and has been shown to decrease lower leg pain and improve circulatory function in individuals with this problem. It is as effective as support stockings at removing fluid from your lower legs. I explain in detail how this nutrient helps your veins and fluid retention issues in my article, Horse Chestnut for Your Veins. I have also reported that aescin’s modulation of the key inflammatory gene signal, NF-kappa B, protects against stroke, can lower leptin while boosting HDL Cholesterol, and may help chemo drugs work better.

This new study is important because your liver is constantly cleaning your blood. It appears that aescin is able to help in multiple ways by reducing inflammation in the liver, boosting the antioxidant defense system, and even lowering elevated liver enzymes – all in response to toxic LPS. This would help individuals fight infection better and not get so toxic from infection, while specifically helping the liver to perform better.

It appears that the benefits of horse chestnut are more than its best documented role in helping the veins in your legs and reducing leg fluid retention. Its anti-inflammatory mechanisms are highly protective around your body and help contribute to your overall ability to cope with wear and tear.

Sunday, December 11, 2011  -  Byron Richards, CCN
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