Aging appears to begin between the ages of 27 and 35 when the production of enzymes that dissolve protein begins to diminish. Enzymes are widely recognized for their importance in digesting food. They also break up circulating immune complexes in the blood. Enzymes can act to prevent too much fibrin from being deposited in wounds, fractures and joints. These enzymes also remove necrotic debris and excess fibrin from the blood stream. Immune system regulation can also be accomplished with enzymes. Most of the development of systemic enzyme therapy was carried out in the Far East and Europe. Enzyme therapy is a prime example of a situation in which US medicine is missing the boat due to a lack o of awareness of what the rest of the world is doing and our unwillingness to use therapies not made by “big pharma.” Enzymes can not be patented so they are of little interest to drug companies.

The proteolytic enzymes used in enzyme therapy dissolve fibrin. When strong proteolytic enzymes are in an enzyme preparation, they can be powerful enough in their action to actually gradually digest scar tissue away. This takes time to occur, of course, but eventually all the scar tissue may disappear.

Sometimes when the body deposits excess fibrin in a tissue the tendon sheaths become thickened and the free movement of a tendon back and forth fails to occur with the tendon getting caught in the fibrous tissue (e.g. trigger finger, Dupytron’s contracture of the palm, etc.) and failure of normal function occurs. Tissues containing excess fibrin are weak because they do not provide adequate space for the epithelial tissue that normally grows through the whole fibrin matrix, producing strength.

These tissues with excess fibrin have restricted motion if joints are involved and will have diminished size and function if the scarring involves an internal organ(e.g. heart after infarction, kidney after a clot to a kidney artery, pancreas after episode of pancreatitis, etc.)

Systemic enzymes have a unique feature. Side effects do not occur with systemic enzymes. This means that raising the dosage to massive levels does not cause any problems unlike pharmaceutical drugs. The initial dosage, which is often one potent enzyme pill three daily taken 45 minutes before or 45 minutes after a meal, can be raised by three tablets daily every few days until the desired therapeutic response develops.. A person given more than 3700 enzyme tablets in one day experienced only diarrhea from this massive capsule intake.

A second interesting facet of systemic enzymes is that their effects on coagulation intensify the actions of blood thinning drugs like coumadin. Fibrin digests with enzymes which dissolves blood clots.Persons on anti-coagulant drugs and individuals with hemophilia may have more intense bleeding with enzyme therapy, and should avoid using enzymes.

Use of Vitalzym in Disease Conditions

Vitalzyme + is an enzyme formulation that contains protease, serrapeptase, papain, bromelain, amylase, lipase, rutin and amia, which is a rich source of vitamin C. Serrapeptase is a unique proteolytic enzyme isolated from non-pathogenic enterobacteria Serratia E 15 that has superior anti-inflammatory action[1] when compared to other proteolytic enzymes. Serrapeptase is the enzyme found in the intestine of the silkworm that permits the silkworm to break out of the cocoon.

In addition to breaking down fibrin deposits, Vitalzyme+ reduces inflammation, removes and filters viruses from the blood, balances the immune system, and removes toxins from the blood. The systemic effects of enzymes can be used to prevent and resolve many diseases. The rutin contained in Vitalzym has valuable properties. Rutin is a bioflavinoid which composes 4-6% of buckwheat. Rutin strengthens and controls the permeability of blood vessels and capillary walls. This turns weak blood vessels into strong ones that are less likely to bleed. Rutin lowers the blood pressure and slows aging.
Bioflavinoids, such as rutin, quercitin, and hesperidin, are powerful antioxidants that effectively combat free radicals believed to cause 90% of diseases(cancer, arteriosclerosus, arthritis, aging etc.) Other enzyme formulations such as Nattokinase, Lumbrokinase, and Wobenzym contain potent enzymes such as chymotrypsin which make them very effective.

Many articles have been written recently extolling the virtues of serrapeptase. Serrapeptase has anti-inflammatory, anti-edema, and fibrinolytic properties. A study in otolaryngological patients from many centers in Italy disclosed that serrapeptase was very effective in alleviating thick infected secretions.[2] Ninety one percent of those taking serrapeptase reported good to excellent results compared to 22% in the control subjects. Knee cartilage operations were followed by 50% less swelling[2] in the group of patients taking serrapeptase. Patients with fibrocystic breast pain[3] reported 85% marked to moderate improvement compared to 65% not receiving serrapeptase. Twenty patients (average age 39) with carpal tunnel syndrome[4] were given 10 mg of serrapeptase twice daily. Thirteen of these were better with electrophysiologic proof of recovery.

Enzyme Therapy In Malignancies

In Europe, therapy of malignancies usually includes enzymes in large dosage which has lengthened survival. Enzyme preparations are carefully formulated so they are able to avoid dissolving in stomach acid and thus are available to get into the blood without being destroyed.

In cancer cases, the cancer cells are surrounded by a layer of fibrin which may be up to 15 times thicker than the layer of fibrin that surrounds normal cells. This fibrin layer permits these malignant cells to escape destruction by killer immune cells, which are unable to detect the cancer cell antigens. The systemic enzymes are able to remove this fibrin coating, permitting the immune cells to again kill the tumor cells. Additionally, immune cells become stimulated by enzymes to increase the production of tumor necrosis factor which can attack tumor cells, as well as cells infected by viruses. This is vital to cancer defense. Systemic immune therapy has prolonged life for many patients, and in the case of cancer of the pancreas, Dr. Wyba states that about one-third of cases have been cured using Wobenzyme. The enzymes must not be stopped or the cancer recurs. The dose may need to be as much as 30 pills three times daily. We think it may be wise to include enzymes along with other therapies in treating cancer.

Enzyme Therapy in Infections

The human body reacts to infections by increasing the viscosity of the blood. This slows the flow of blood and increases the clotting tendency of the blood. At times, the clotting tendency is so exaggerated in infections, malignancies and other disease states that there is widespread occurrence of fibrin clots all over the body (disseminated intravascular coagulation). In this state, all of the blood’s substances that are needed to cause the blood to clot become consumed, resulting in no ability to clot. This leads to widespread hemorrhagic are at the same time there is a multitude of clots. Systemic enzyme therapy stops the clotting tendency of blood that occurs in infections by its action to dissolve fibrin. There is an increased risk of heart attacks and strokes immediately after acute infections (Chlamydia, Cocksackie viruses, etc.) and in persons suffering from gingivitis.

Viral and Bacterial Infections

Many infectious problems that trouble humans come to light when a dormant virus becomes activated after residing harmlessly for many years. A good example of this is herpes zoster skin infection developing in patients who had recovered from an old chicken pox viral infection (varicella zoster) many years previously. Herpes viruses may lie dormant for many years, only to produce very painful neuritis at a later date.. This may follow an acute illness or any event that injures the immune system(chemotherapy).

When a virus contacts a human cell, the external coating connects to the cell, and the virus becomes able to contact DNA. This connection to DNA permits the virus to reproduce in a rapid manner. Proteolytic enzymes consume the exterior coating of a virus rendering the virus permanently inert. To recover from a viral infection requires that enough enzymes be taken to get ahead of the rapid viral replication within cells, This may require 5-10 capsules of Vitalzyme + three times daily or more.

Biofilm Protection for Bacterial Infection Involving Prosthetic Substances

One of the problems plaguing medicine currently is infection of prosthetic substances placed in the body(prosthetic hips, knees, heart valves. etc.) These infected prosthetic parts often need to be replaced, as their infection can not be eliminated. Bacteria are able to create a biofilm that prevents antibiotic drugs from reaching and killing them. A similar problem exists in heart valve infections, where frequently an emergency replacement of an infected valve leaflet becomes the only way to save the patient’s life. The proteolytic enzyme serrapeptase was shown to enhance the killing activity of the antibiotic Ofloxin in cultures and to prevent the formation of biofilms.[5] This prevention of biofilms could become very valuable in treating these problem infections.

Enzyme Therapy in Allergic Diseases

There is an inflammatory component to the asthmatic attack. Use of enzymes during an acute episode should be effective therapy in many persons. Decreasing the volume of secretions and causing the secretions to become less viscous so they could be easier to cough up is also beneficial. Maintaining a low dosage of enzymes, 2-3 capsules daily, should also create an environment in which it would be more difficult for a new attack of asthma to get started.

The allergenic pollens irritating the nose in allergic rhinitis(hay fever) cause the production of considerable mucous secretions. Taking enzymes should decrease the volume of these secretions and thus alleviate the symptoms. As in asthma, taking 2-3 enzyme capsules daily could prove valuable by making it more difficult for hay fever symptoms to be initiated.

Use of Enzymes in Painful Conditions

Proteolytic enzymes are able to block the release of pain producing amines from tissues that have inflammation. This elimination of pain benefits many conditions. The disability of migraine headaches can usually be helped by enzyme therapy. Sinus headaches can be alleviated by enzymes, which decrease and liquefy secretions that contribute to the pain. A group of 59 patients with acute and chronic sinusitis were assigned to receive either the enzyme bromelain or placebo along with conventional therapy (antibiotics, decongestants, etc.) The group getting bromelain seemed to improve because it dissolved fibrin leading to improved absorption of edema fluid, thus enabling greater penetration of immune system components. Obviously, one of the more valuable uses for enzymes is to relieve the pain in arthritic conditions, bursitis, and synovitis.

Lung Disease and Enzyme Therapy

Pulmonary Fibrosis: In pulmonary fibrosis the thin, filmy, alveolar membrane, which permits oxygen to enter the bloodstream and enables carbon dioxide to pass from the blood into the lung air spaces , becomes progressively thickened by the laying down of fibrin deposits on the alveolar membrane. These thickened alveoli do not permit normal oxygen for carbon dioxide exchange in the lung. Shortness of breath then appears with exertion.

Many disease states can cause a chest x-ray appearance identical with that of pulmonary fibrosis. These conditions include cancer, infections, inhaled irritants(asbestosis, silicosis, beryllium, etc.), sarcoidosis, diseases of connective tissue (lupus, rheumatoid arthritis, scleroderma), and adverse drug reactions (more than 50 can cause fibrosis including 14 chemotherapy drugs, sulfa, penicillin, furadantin, hydralazine, aprèsaline, gold, chlorpropamide, allopurinol, hydrochlorthiazide, and dilantin). Standard therapy for pulmonary fibrosis includes courses of cortisone and immunosuppressive drugs (Imuran etc.) if cortisone fails to benefit.

Since pulmonary fibrosis has progressive scarring and an inflammatory reaction in the alveoli, therapy with systemic enzymes that digest fibrotic tissue and block the inflammatory reaction should be a safe rational approach. Vitalzym + is helping patients with pulmonary fibrosis. Start with 3 capsules three times daily on an empty stomach and raise the dosage at regular intervals until improvement is noted.

Sarcoidosis A disease of unknown cause, sarcoidosis is more common in Afro-American than Caucasians. The disease causes nodules and scarring in the involved organs, Sarcoidosis is often discovered by a routine chest xray revealing shadows in an adult with no symptoms. The lung is the most common organ involved with the disease but the eyes, skin, nervous system, bones, and joints may also be involved.

Lung symptoms may include cough, shortness of breath and wheezing. When the lung symptoms are advanced or the disease involves critical structures(eyes, nervous system) cortisone therapy is usually effective. Often it is impossible to discontinue cortisone, which may need to be maintained in low dosage.

A promising therapy for sarcoidosis is systemic enzymes for a trial period of 2-3 months. The inflammatory granulomas and scar tissue(fibrosis) in the lung, eyes, bones, joints and skin might very well be terminated by this therapy which is much safer than cortisone. Regular increase in enzyme dosage will reach levels where resolution of fibrosis can occur.

Use of Enzymes in Arthritic Diseases

Enzymatic therapy can benefit all forms of arthritis by reducing inflammation, alleviating pain, and stopping the circulation of inflammation causing immune complexes. For these reasons many arthritis products contain enzymes(bromelain,papain, etc.) Wherever there is pain there is inflammation which can be blocked by enzymes.

Systemic Lupus Erythematosus

A key feature of SLE is allergic reactions in body tissues (auto-immunity). Circulating immune complexes are routine, and the sites where they deposit determine the symptoms of this disease, (lining membranes overlying lung, heart, abdomen, joints, brain, skin, etc,) A trial of systemic enzymes could remove these circulating immune complexes from the blood of the SLE patient.
Several months of enzyme therapy might have a dramatically beneficial effect on the disease. High dosage initially is a good idea.


Fibromyalgia (FM) afflicts approximately 6 million persons in the USA, predominately women in the 20-40 age bracket. FM is characterized by severe muscle pain, tenderness in 18 points where muscle and tendons merge, fatigue, headaches(50%), and severely impaired sleep.

This common condition afflicts nine times more women than men. These persons are troubled by severe unrelenting pain in areas where tendons join bone. Estrogen causes the deposition of fibrin, which can lead to impaired circulation with sludgy blood flow in the areas of fibrin accumulation. Hyperestrogenemia is common in our modern world.

The etiology of fibromyalgia is complex and not completely understood at this time. A multitude of infectious organisms have been found using high –resolution microscopy. The list of infectious pathogens identified in patients with fibromyalgia includes mycoplasma, anerobic bacteria, several types of fungi, and borrelia burgdorfi (Bb). The fungi appear to play an important role in causing endocrine dysfunction, presumably by the mechanism of releasing neurotoxic substances, into the bloodstream, which disrupt the normal function of the hypothalamus producing hypothyroidism and hypo-adrenal function.

Several patients with fibromyalgia have recovered when taking the Japanese enzyme nattokinase made from fermented soybeans. This improvement may have occurred because the enzymes are able to reverse the adverse effects of fibrin production and thus improve the circulation of blood into fibrotic areas. Other enzyme products (Wobenzyme, Vitalzyme, Lumrokinase) might also be valuable by the same mechanism.

Systemic Enzymes in Kidney Diseases

Acute and chronic glomerulonephritis are common kidney diseases. The patient with acute nephritis often has high blood pressure, swelling of the extremities, and blood and protein in the urine. This disease is considered frequently to be the result of an allergic reaction to the presence of streptococcal or other bacterial organisms in the body. Circulating immune antigen antibody complexes are common, and if the disease does not soon spontaneously resolve, scarring and fibrin deposits in the kidney’s urine forming units (glomeruli) are found.

Chronic damage to the kidney in time may lead to uremia, dialysis, and kidney transplantation. The presence of fibrin deposits, scarring of the kidney and circulating immune complexes makes a course of systemic enzyme therapy a good choice for these patients. This therapy is safe and has good potential to be beneficial.

Other kidney diseases that could also be helped by systemic enzymes include Goodpasture’s syndrome, Henoch-Schoenlein purpura, Mixed cryoglobulinemia, IGA nephropathy, periarteritis nodosa, Wegener’s granulomatosis, hemolytic uremic syndrome, hypersensitivity vasculitis, interstitial nephritis (drugs may cause this—antibiotics like gentamycin, vancomycin, amphotericin, etc., phenacetin, non-steroidal anti-inflammatory agents like naprosyn and indocin, and many chemotherapy drugs, —or infection such as pyelonephritis).The pathology of swelling, inflammation and scarring(fibrosis) in all these conditions could be helped by systemic enzymes.

Use of Enzymes in Trauma

Serious injuries are usually followed by massive swelling and considerable pain. Immediate therapy with enzymes can dramatically shorten the disability and quickly resolve the pain. The key to this therapy is to take enough enzyme immediately as the battle is being lost when swelling and pain appear. Rehabilitation and recovery will be delayed. It is far more effective to use too much enzymes early than to have to frequently raise the enzyme dose because pain and swelling is spreading.

Lowering the enzyme dose is simple. This may call for using 15 to 20 capsules of systemic enzymes three times daily for injuries such as severe auto accidents with multiple fractures, dislocated hips or shoulders and following knee and hip replacements. Most likely the recovery period from joint replacement surgery could be significantly shortened if orthopedic surgeons used systemic enzymes. Patients taking enzyme therapy should stop this therapy 24-36 hours prior to elective surgery and resume the therapy 24-36 hours after the operation. Taking enzymes during the immediate post-operative period could prevent the normal occlusion by fibrin in small blood vessel lacerations, which might produce oozing of blood with anemia postoperatively. German surgeons have effectively used enzymes in surgical patients for many years. Remember it is more effective to decrease the dosage when things are going well than to increase the dose when pain and swelling have gained the upper hand. Large doses of enzymes do not cause side effects.

My personal experience made me a believer in enzyme therapy. One of my molars needed a root canal, which I knew was dangerous in my diabetic state as it always creates an abscess in the root canal tooth which can never be sterilized. The extraction of the molar tooth was quite difficult as it required continuous effort by 2 dentists for 90 minutes. One of them later admitted it was one of the most difficult extractions he had ever performed. Within an hour I began taking 900 mg of bromelain three times daily (large dose). Neither pain or swelling appeared which surprised the dentist.

Enzymes and Estrogen Excess States (Fibrocystic Breasts, Fibroids of the Uterus, Endometriosis, Polycystic Ovaries, Benign Prostatic Hypertrophy, Cancers of Breast, Prostate, Uterus, Ovary).

Estrogens are able to produce fibrosis, and this capability leads to these painful disorders.

Several factors are producing the estrogen excess status that is widespread in the developed world:

Breakdown of petrochemicals, pesticides, herbicides, plastics, sodium lauryl sulphate from cosmetics, propylene glycol, vehicle exhaust, and other agents into estrogenic substances in the human body.
Extensive use of estrogenic hormones to expedite growth of cattle and chicken.
Use of powerful pharmaceutical estrogens(Premarin) and oral contraceptive pills that magnify the existing estrogen excess in the female body.
Misuse of estrogens in therapy as a sole agent instead of combining natural estrogen with safe natural progesterone, which nullifies the adverse effects of estrogen alone therapy.
Diets high in sugar and dairy products, and low in fiber result in recycling estrogen into the body instead of elimination in the stools which occurs on high dairy diets. These diets also interfere with proper production of progesterone by the corpus luteum of the ovary.

Because of this state of estrogen excess, fibrosis, and painful cysts appear in breast tissue(fibrocystic disease of the breast). Many women cease ovulation 10 or more years before menopause due to this estrogen excess state. These women are thus unable to benefit from the estrogen ameliorating effects of progesterone production by the corpus luteum. The heavy intractable bleeding they experience often leads to hysterectomy. Existing fibroids in the uterus tend to appear and steadily enlarge under the stimulation of excessive amounts of estrogen.

Many women suffer from endometriosis, which seems to be produced by retrograde flow of blood into the peritoneal cavity at the time of menstruation. This fluid entering the peritoneal cavity contains blood and shed endometrial cells. A profound inflammatory reaction appears which often results in severe pain. Recurring episodes of this problem leads to “chocolate cysts” and scarring at the site of these peritoneal deposits. An unfortunate result of endometriosis is scarring of the fallopian tubes and sterility. The patient with endometriosis might need 5 or more capsules of enzymes three times daily until their pain disappears. Some women can ascertain when menstruation is imminent. These women could possibly be helped by starting enzymes before they notice the onset of menstrual pain.

Enzyme therapy can stop the development and enlargement of existing uterine fibroids. Patients with fibrocystic breast disease and enlarging fibroids should stay on enough enzyme therapy to prevent symptoms. Whether high doses of enzyme therapy over prolonged periods of time could completely dissolve large fibroids is not known, but it might well do so and appears to be worth a trial.

Another worthwhile approach to estrogen excess uses enzymes (DeAromatase[1]) which effectively corrects this problem by blocking the actions of the enzymes aromatase and 5 alpha reductase so that estradiol, testosterone and progesterone levels return to normal. Without this enzyme therapy androstenedione and testosterone are steadily converted into estrogen (estradiol). This raises already elevated levels of estradiol and diminishes already low levels of testosterone. To make matters even worse the enzyme 5 alpha reductase at the same time is converting testosterone into di-hydrotestosterone the substance believed to be responsible for some prostate gland enlargement.
When DeAromatase therapy comes on the scene progesterone begins to inhibit the action on 5 alpha reductase causing rising testosterone levels and reducing the amount of estrogen formed.
Both testosterone and progesterone promote the p53 gene leading to normal healthy cell death (apoptosis) while estradiol promotes the Bel 2 oncogene which blocks normal apoptosis (cellular death) and causes cancer.

Arteriosclerosis and Enzyme Therapy

One of the potentially most useful areas for enzymes is in stopping the progression, and hopefully promoting regression of arteriosclerotic plaques. Excessive clotting caused by infectious inflammatory reactions in the body is now believed to play an important role in the causation of arteriosclerosis. This can be reversed by the fibrin lysis occurring during enzyme therapy. Three cases illustrating clear improvement in arteriosclerotic symptoms after enzyme therapy are presented later in this article.


Some patients develop thick unsightly scars(keloida) after surgery or injuries. Taking systemic enzymes following the surgery can prevent this excessive scar formation. Knowledgeable plastic surgeons use enzymes to minimize scar formation after surgery.

Case Reports

Case 1 A patient with a hip defect had considerable pain and difficulty walking. After starting serrapeptase he became completely pain free and walked in a normal fashion for the first time in years.

Case 2 A 34-year old male had a bad family history for vascular disease(three grandparents died of vascular disease at 56. 56, and 63 years of age, and his mother died of a heart attack at age 62). This patient took a prolonged course of intravenous chelation along with measures to correct arterial disease (high dosage vitamin C). He then had an ultrasound study of his carotid arteries , which revealed 12% narrowing of the right carotid artery and 14% narrowing of the left carotid artery. The site where the right carotid artery bifurcates into two arteries had a 24% narrowing. He increased his vitamin C dosage to 10-12 grams daily, started taking 1.5 grams of lysine three times daily, and also took folic acid, B12 sublingually, twice daily, B6, and trimethylglycine. Serrapeptase 10 mg twice daily was begun. A repeat carotid artery study in 18 months disclosed complete resolution of all plaques in the carotid arteries. Vitamin K2 45 mcg. daily which removes calcium from arteries and moves it into bones would probably also have been a worthwhile therapy.

Case 3 In 1945, a six year old child and a friend fell into a pocket of radioactivity (about 650,000 millicuries of Iodine 131 exposure) while playing a game. He immediately noticed burning in his lungs and trouble breathing. His friend died within a few months. And the girl who pulled him out of the hole died of the effects of radioactivity at age 35. He developed severe dyspnea with any exertion along with wheezing and scarring of his lungs and other organs.

At age 63, a knowledgeable physician urged him to take Vitalzym as, “It will dissolve the scar tissue.” His pulmonary function improved by 25% and he can now climb two flights of stairs without difficulty.

Case 4 A man with severe angina and claudication was not improved by laser therapy, robotic therapy, or endarterectomies of his coronary arteries. Therapy with ozone saunas and calcium EDTA chelation relieved his symptoms, but with exertion he still had problems. After a few days of Vitazlym, along with ozone saunas and chelation he was able to resume hunting. fishing, and hiking without any pain in his chest or legs.

Case 5 A man with angina at rest and claudication after walking 15 feet improved with calcium EDTA and ozone saunas. Within 2 days on Vitalzym he was able to walk to the grocery store without stopping or having either chest or leg pain.

Case 6 This woman had temporo-mandibular joint pain for several years with no response to laser surgery surgery, physical therapy, or acupuncture. Sleeping and eating were impaired due to pain. After two months of Vitalzym, she was pain free and much improved.

Case 7 This mother had her 18 month old son do a back flip onto her nose and the back of his head. smashed her nose. She was in severe pain with immediate swelling of her nose, cheeks, and eyes. She placed an ice pack on her face and took 20 Vitalzym. The swelling began to disappear and the pain was nearly gone by the following morning. After 10 more Vitalzym capsules the next morning, the pain and swelling disappeared.

Hospital Formularies and Systemic Enzymes

Because systemic enzyme therapy was developed in Europe and the Far East, most US physicians are certainly unfamiliar with it. This means that patients landing in hospitals with some of these previously discussed problems may find themselves in an institution that does not stock systemic enzymes. Hospital formularies lean heavily toward pharmaceutical drugs, so the systemic enzymes may not be in the formulary unless unless the hospital is staffed by some knowledgeable plastic surgeons. Furthermore, hospital formularies do not like to stock a product that will be used by only one patient as unused portions of the product may expire. Even without the availability of enzymes in the formulary, some hospitals will permit patients to take outside therapy if the attending physician gives his or her approval.

More Research Needed

In reviewing the available literature about enzyme therapy, it is apparent that not all patients improve. Most studies show 75-80% of patients clearly improve. This raises a very important question. Would higher doses over a longer time frame have benefited those patients who failed to respond to the initial enzyme dosage?

The safety of systemic enzymes in high dosages means that we cannot be certain systemic enzymes would not help a patient until high doses have been tried over longer periods of time. It appears to me that this is particularly relevant in diseases like sarcoidosis, pulmonary fibrosis, scleroderma and uterine fibroids where there is such extensive scarring it would not be reasonable to expect prompt resolution. There is a possibility that severe scarring may not be reversible, but this needs to be proven as reversal of scarring in these serious health problems could be of immense value to the afflicted patients.

Practical Aspects of Enzyme Therapy

Tylenol(acetaminophen) is a very dangerous drug that, in my opinion, should never have been released. This drug is nearly universally found in US homes. Acetaminophen accelerates aging and can cause death from acute necrosis of the liver in young healthy persons who use this drug because of an acute viral infection. None of us needs speeding up of the aging process. Enzymes are far safer than this therapy for pain.

Having Lumbrokinase, Nattokinase, Wobenzyme, Bromelain or Vitazym+ in your home provides a therapy well qualified to alleviate a wide variety of painful disorders without any danger .to the user. The usage of enzyme therapy should increase as more health care practitioners learn about this exciting therapy. Vitalzym + and DeAromatase are available from Phone 1-800-416-2806.


1- Howenstine, J. A Physicians Guide To Natural Health Products That Work, or call 1-800-416-2806


1, Mazzone A. et al Evaluation of serratia peptidase in acute or chronic inflammation of otolaryngogo;y pathology: A multi-cetre, double-blind, randomized trial versus placebo. J Int Med Res 1990, 379-88
2, Esch PM, et al Reduction of postoperative swelling objective measurement of the upper ankle joint in treatment with serrapeptase ——- A prospective study (German) Fortschr Med. 1989; 107(4)67-8, 71-2
3, Kee WH et al The treatment of breast engorgement with serrapeptase (Danzen) a randomized double blind controlled trial Singapore MJ 1989; 48-54
4, Panaguriya A., et al A preliminary trial of serrapeptase in patients with carpal tunnel syndrome. J Assoc Physician India; 47(12):170-172
5, Selan L et al Protolutic Enzymes: A new treatment strategy for prosthetic infections? Antimicro Agents Chemother, 1993;37(12):2618-21


Dr. James A. Howenstine is a board certified specialist in internal medicine. The Second Edition of his book A Physicians Guide To Natural Health Products That Work is available.

Dr. Howenstine can be reached by writing Dr. James Howenstine C/O Remarsa USA SB 37, P.O. Box 25292, Miami, Fl. 33102-5292.


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