Alpha lipoic acid (ALA) is a virtually unknown nutrient. It is a naturally occurring thiol antioxidant, or simply stated, a sulfur containing chemical produced in plants and animals.1,2 It has been shown to have a remarkable ability to regenerate other major anti-oxidants and protect the body from oxidative stress. Research has also shown that it has the potential to outperform chemotherapy in its ability to reduce cancer cell formation; with little to no side-effects or collateral damage.
Alpha lipoic acid is found in food and many alternative health doctors use higher dose supplemental form to help those with diabetes, neurodegenerative conditions, auto-immune diseases, cancer, and heart disease. Alpha lipoic acid in supplemental form is also used to improve human performance in otherwise healthy individuals.
Where Do We Find Alpha Lipoic Acid? (more…)
(Health Secrets) Can you imagine a supplement that protects every organ in the human body and has no significant side effects? This is the kind of claim that gets the FDA after the supplement industry, but in the case of lipoic acid, there’s plenty of research showing this claim may be true. What makes lipoic acid so special? Unlike drugs which possess a singularly defined molecular mechanism of action, lipoic acid is capable of producing multiple effects from its influence on a single gene.
Lipoic acid is a naturally occurring substance, essential for the function of different enzymes that take part in the mitochondria’s oxidative metabolism. (The mitochondria is the tiny furnace contained in each cell, in which food is burned and energy is produced – it is at the very core of life.) The excess production of free radicals occurring in this process results in oxidative stress being a big factor in the development of degenerative diseases. Lipoic acid has many biochemical functions in the human body to turn this process around:
- Functioning as antioxidants
- Chelating active metal ions
- Protecting against oxidized forms of other antioxidants such as vitamins C and E
- Modulating signaling transduction in several pathways
Scientists still haven’t managed to discover the Fountain of Youth, but there are four critical nutrients and supplements that are vital to your health and will help you lead a long and healthy life. They are:
• Co-enzyme Q10
• Alpha-Lipoic Acid (more…)
(Health Secrets Newsletter) Alpha lipoic acid, or ALA, is a potent and versatile antioxidant that also serves to convert blood sugar into metabolic energy. In addition, recent research has shown lipoic acid’s power to help repair nerve damage and possibly protect against Alzheimer’s and declining vision. There are many more health issues helped by ALA than most of us know. (more…)
Body weight is one of the most basic issues of human life. Self-esteem, acceptance among peers– and perhaps lifelong success or failure—are, unfortunately, all tied to our physical appearance. Medically speaking, not all overweight people are obese. Obesity is defined as weight that exceeds 15 percent of normal weight for height and body type. “Morbid” obesity exceeds 20 percent of optimum weight. The long-term health implications are well known, in fact, obesity is considered an outright disease. Life expectancy may be decreased in overweight and obese individuals. An obese person is at high risk for a number of serious health problems, including heart disease, high blood pressure, stroke, varicose veins, psychological stress, osteoarthritis, high cholesterol, and diabetes. (more…)
Diabetes is a devastating disease that results from an inability to properly metabolize glucose resulting from poor insulin function. Researchers writing in the Journal of Clinical Biochemistry and Nutrition found that the naturally occurring cellular antioxidant, alpha lipoic acid, has the ability to correct abnormal insulin signaling and resistance that are known to promote disease development. Lipoic acid is shown to rejuvenate energy production in the critical mitochondria and to enhance the metabolism of sugars and carbohydrates thus restoring proper insulin activity. Most health-minded individuals will need to supplement with the biologically active `R` form of this critical antioxidant to effectively thwart metabolic disease and diabetes progression. (more…)
Supplemental use of R-alpha Lipoic Acid1 has the therapeutic potential to correct abnormal insulin signaling and insulin resistance, key factors to correct in individuals stuck at a higher-than-normal body weight.
Once a person quits poisoning themself by eating too much food, then various nutrients can help to correct the mess and tangle of metabolic signals that are in a funk. R-alpha lipoic acid shines in this regard as it rejuvenates energy production in the mitochondria of cells, it enhances the metabolism of carbohydrates, fats, and protein, it rebalances antioxidant enzymes so they work properly again, it protects nerves from damage, and it can restore defunct insulin signaling.
The new science shows a clear link between the antioxidant status within a cell and that cell’s ability to have proper insulin function. R-alpha lipoic acid has a profound influence on other antioxidant nutrients and enzymes, helping to put them into a state of efficient balance so they can work properly. As a result, multiple gene signals relating to insulin and glucose metabolism are improved. These findings have profound implications for any overweight person, especially type 2 diabetics.
In our old way of thinking about this issue, it was simply a matter of too many calories being pushed at cells and the cells rejecting them because no more fuel was needed. The new gene science is showing an amazing level of regulation of insulin based on a cell’s antioxidant status. This means that a cell also doesn’t want sugar if it doesn’t have enough antioxidants to protect the cell as the sugar is metabolized. Within a cell, sugar is like logs burning in the fireplace with the byproduct of energy production. Antioxidants are like the fireplace screen that keeps the fire where it is supposed to be. Is it any wonder that just about every overweight person is lacking antioxidants?
Wednesday, July 13, 2011 – Byron Richards, CCN
Referenced Studies: ^ R Alpha Lipoic Acid, Antioxidant Status, and Insulin Signaling J Clin Biochem Nutr. Packer L, Cadenas E