Medication-Induced Mitochondrial Damage

drug induced mitochondrial damage

Damage to mitochondria is understood to play a role in the development of a wide range of seemingly unrelated disorders such as schizophrenia, Alzheimer’s, cardiovascular disease, diabetes, and others. Mitochondrial damage is also a hallmark of ME/CFS and Fibromyalgia.

Common causes of mitochondrial dysfunction in ME/CFS and Fibromyalgia are numerous. They include:

  • Dysbiosis
  • Chronic viral infections
  • Metabolic dysfunction (poor insulin control, nutrient depletion)
  • Toxin exposure (metals, mold, other environmental factors)

Another cause of mitochondrial dysfunction that is less frequently mentioned is medication usage. Mitochondrial toxicity testing is NOT required by the FDA before a drug is approved. Medications can hinder mitochondria through direct or indirect mechanisms.

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