Curry Spice Compound May Combat Parkinson’s Disease

Curry Spice Compound May Combat Parkinson's Disease

Affecting more than 4 million people worldwide, Parkinson’s Disease (PD) is a chronic motor system disorder characterized by tremor, rigidity; bradykinesia (slowness of movement) and postural instability.  There presently is no cure, and medications, while offering symptom control, can become less effective over time. Basir Ahmad, from again State University (Michigan, USA, and colleagues revealed that curcumin, the compound that gives the spice turmeric its bright yellow color, is effective at preventing clumping of the protein, alpha-synuclein, involved in Parkinson’s disease, and increases its reconfiguration rate, particularly at high temperatures. Consequently, the study authors conclude that: “Curcumin rescues the protein from aggregation by making the protein more diffusive.” (more…)

Curcumin Outperforms Pharmaceuticals and Prevents Disease Without Side Effects

Adding to the wealth of research confirming that high antioxidant spices protect the body and prevent disease more effectively than drug based treatments, a Michigan State University researcher has found that curcumin, a compound found in the spice turmeric, is proving effective at preventing clumping of a protein involved in Parkinson’s disease.

One of the most comprehensive summaries of a review of 700 turmeric studies to date was published by the respected ethnobotanist James A. Duke, Phd. He showed that turmeric appears to outperform many pharmaceuticals in its effects against several chronic, debilitating diseases, and does so with virtually no adverse side effects. (more…)

Mitochondria Gone Bad

Mitochondria are among the small structures called organelles that reside within a cell. Known as the cells’ powerhouses, mitochondria extract energy from fuels such as glucose in the presence of oxygen to produce a molecule called adenosine triphosphate, or ATP (green), which provides energy for the cell. In the process, mitochondria generate potentially dangerous free radicals (red).Illustration: Nicolle Rager FullerThe patient, known as only “MBM,” was just 7 years old the first time doctors saw her. She had always been prone to night sweats, but now excessive perspiration was forcing her to change clothes several times a day. She was endlessly thirsty, fatigued and losing weight despite a voracious appetite. A dozen years later, at age 19, doctors checked her into a hospital, thinking she had some kind of unusual metabolic condition. After aggressive treatment with drugs, her symptoms improved, but only for a short time, and the next year surgeons removed most of her thyroid. When she was 35 — gaunt, weak and losing hair — doctors began searching every tissue of her body for a diagnosis. (more…)